Survival In the World of Beasts - Chapter 106 Outside of Li Dingxi (1)

January 4, 20X7

Just saw Daren's reply, he read the information I sent, and he couldn't do anything in the case of Xiao Xiao. I thanked him for his comfort, but the pain in it, except for my relatives, really couldn't be said easily.

Now I’m glad that I didn’t tell my mother about contacting him. Every time I tried hopefully, she told me that Xiao Xiao would wake up, but every time we returned from disappointment, she was the hardest hit.

Watching her hair turn white day by day, I don't know how long we can hold on. I have almost contacted all my old knowledge in academia. I have found nothing and I am really tired.

January 7, 20X7

The girl brought flowers again. After so many years, Xiao Xiao’s classmates would often come to visit him, but she came the most.

I know that she has always felt guilty about the accident that year, but I can’t blame her. The accident made Xiao Xiao look like this. His classmates all blame themselves so much. They are all good children. I can’t blame any of them. People, only to blame for the impermanence of fate, the will of God, Xiao Xiao has always been such a good child...

February 1, 20X7

I still made this decision, went through the discharge formalities for Xiao Xiao, and received it from my laboratory. My mother always disagrees. After so many failures, I don't know if she will compromise, but I would rather she know nothing. I'll make this decision. I only told her that I sent Xiao Xiao to the UK, where Lee would provide him with the best convalescent environment.

I have decided that if he can't wake up after the last attempt, I would rather let him end this life. As with others like this, with life-sustaining equipment all over the body and going down without knowing it, it would be better for me to end it all.

My mother would definitely not agree, but all this is really enough. For Xiaoxiao, me or her, such a long and hopeless day is really enough.

I never thought that my research results would one day be tried on my relatives... But this is really the last hope. If the gods and Buddhas are alive, please bless him to wake up. He has always been such a good one. My child, he has never done anything bad, he is still so young, his future is full of hope, and his life has just begun... Dad, if you are alive in the sky, please bless me and Xiao Xiao!

April 18, 20X7

Lee came back. After I had a big fight with him and left the experimental group, everyone has no contact. After so many years, I don't know why he came to China again.

I’m a little confused. The experiment plan of Xiao Xiao over the past few months has filled my mind. I have not made any progress. I feel that my emotions are a bit wrong. The assistant’s expression today makes me realize that this will not work. I also need to adjust. I Accepted Lee's invitation.

We ate a meal at the restaurant I used to take him to. Now he will not be like when he came for the first time, with his bright yellow skin and black eyes, but he can't speak Chinese well, and he can't use chopsticks.

Seeing him skillfully ordering food with the waiter and arranging the tableware, I was in a daze. I suddenly remembered the many good times before. When Lee came to China for the first time, Xiao Xiao was only six or seven years old. He was learning Chinese and paying for it. It was a mess to teach Xiao Xiao, but it was very successful to let him do mathematics enlightenment for Xiao Xiao, Xiao Xiao always liked mathematics... Forget it, what to do with these things, everything can't go back.

Lee asked me to call him Joe... I refused. Since those times are no longer possible to go back, why bother to maintain those false friendships from the name.

He knew about Xiao Zhao and wanted to see it. I agreed. If Xiao Xiao knew he was here, maybe he would be happy.

April 19, 20X7

I was in a bad mood today. Nothing went well. I had a long queue to the gas station and there was no gas. I parked my car in the public parking lot. It was hailing outside but I didn’t bring an umbrella. Everything is getting more and more abnormal. Xiao Xiao’s experimental plan But there has been no progress. I don't know if I should persist or give up.

Lee came to the lab to see Xiao Xiao in the afternoon. I was in a bad mood and didn't speak much. He didn't say anything. He only looked at Xiao Xiao's information carefully, but I knew it was useless. We are a mentor. I know all of them, and I have asked for help even in those areas that do not overlap with me. It's useless.

April 26, 20X7

I received Lee’s e-mail today. I don’t know if he didn’t text me for anything, he actually wanted to contact me by e-mail. He always has all sorts of weird ideas and does all kinds of things that I can't understand.

His fans always say that one of the reasons for his success is also his charisma, but I think his life is too smooth. He lacks awe and restraint for everything. Sooner or later there will be problems. People always want Awe or something, maybe this difference has long determined that we will part ways.

He sent me a plan and an application form. I read the plan. Lee wants to invite me to join the plan?

In the past few years, I have been busy with Xiaozhu’s affairs. I don’t have much time to pay attention to the international academic community. I only know that he published a paper on SIRT1 on N&S a few years ago, which caused a lot of sensation. After that, he became famous, even in non-academic circles, and Glaxo wanted to hire him as a consultant.

This is actually very easy to understand. The research of SIRT1 has always been a hot spot. After all, it is related to life span and it is normal to attract social attention. Even many newspapers directly named the genes responsible for SIRT1 expression after longevity genes.

I once again pulled out the sensational paper that Lee published on N&S. I admit that this is an amazing discovery. If the experimental data are all true, he did overexpression of SIRT1 in the mice and prolonged their lifespan. , But they are too anxious. All the negative effects and other mechanisms have not been thoroughly studied and published in this way. I am afraid that it will cause unimaginable consequences.

Sure enough, his plan actually wanted to conduct human clinical trials within five years. This kind of thing related to gene expression has so many controversies about crops. He actually wants to realize it in the human body within five years. He doesn't know the bounds of the sky!

Some people say that life science is the closest subject to God, but I feel that the place where we stand is only a short distance from hell. We can try to observe what God has done, but we must never interfere with God's duties. This is what the teacher told me during his lifetime, and I always remember it.

I wrote back to Lee, Xiao Xiao still needs my care, I am afraid I can not participate in this plan. I will not try to convince him that he is such a paranoid guy. I have seen him before, and I am not going to waste this effort.

He quickly replied. He said he was leaving China soon and hoped to see me again.

I deleted the email directly. I didn’t know what to do. I knew his terrible motivation and stubbornness. I would not be persuaded by him. I don’t want to argue with him again. We have different beliefs. It is a matter of parting ways sooner or later, there is no need to overlap.

September 6, 20X7

I have to admit that although Lee's plan was fantastic, it gave me inspiration. The weather was very bad. After several months of heavy rain, the streets were full of water, but this did not affect my mood in the least.

I think I probably found a glimmer of hope for Xiao Xiao to wake up. After so many years, I didn't expect that in the end I would be able to wake Xiao Xiao based on what I learned. This time, I really hold this hope in. Hands.

It takes a lot of steps and trial and error to put it on Xiao Xiao. Maybe it will take a long time, but at least when he wakes up again, he will definitely return to the way he was before the accident. It’s nothing more than this. Good news!

September 8, 20X7

I called my mother and told her that there might be good news from Xiao Xiao. Since Xiao Xiao's accident, she has returned to the small seaside town in her hometown and refused to stay here.

I knew she couldn't put her father down. After all, it was the place where they met and fell in love. She always felt that her father was lonely there and wanted to accompany him more. Before, she just came here to take care of Xiao Xiao.

My mother’s voice sounds so happy, and I feel very guilty. Before Xiao Xiao’s accident, I devoted myself to research and didn’t have much time to accompany her. Xiao Xiao also kept studying and couldn’t go home often. After Xiao Xiao’s accident...she didn’t have much time to relax. Click it.

I think that as soon as the experiment here progresses, I will go back to accompany her and give my father incense.

September 11, 20X7

The flight was cancelled...I couldn't believe it, that the capital city by the sea would be flooded by the sea after the storm, and even the airport would be flooded.

I called my mother frantically, but I couldn't get through.

Many people were stranded at the airport, not only in that city, but many places were affected by successive torrential rains, and flights could not take off. I looked at the rain washing the glass outside, and my heart was anxious.

September 12, 20X7

Fortunately, the response from the authorities was fairly timely. My mother called me. She was already in the temporary settlement. Everything was going well, but the traffic was inconvenient for the time being. I couldn't get her right away. She was still smiling. Comfort me, it's fine when the water recedes.

I can’t go back for a while. It’s probably a public phone over there. I asked my mother some detailed information. The people behind are urging me. I can’t rush over there because of the disaster area. I can only pay attention to the latest news and wait for her to call every day. Up.

September 14, 20X7

I thought it would be fine if the water had gone back, but I didn't expect things to take a turn for the worse. A large flu broke out there after the disaster. I didn't receive a call from my mother today, and I was so anxious.

I have temporarily arranged an assistant to handle the laboratory affairs, and all experimental plans are tentatively decided. I have applied to Professor Qiu in my personal capacity, and I will go to the disaster area immediately with him as a member of the expert group.

At this time, I really felt that I was lacking in skills and couldn't take care of both ends. I could only pause the experiment plan on Xiao Xiao's side and continue until the end of the matter over there.

September 29, 20X7

I'm too tired recently, falling asleep every day, and there is almost no time to record.

The situation is severe, with dozens of deaths. I didn't expect the current virus to mutate so rapidly. I looked at the database data of Professor Qiu and his department, and within a short period of time, the gene chain became completely unrecognizable. If they hadn't kept a detailed record, it would be difficult to know the relationship between this virus and the virus that caused a nationwide pandemic more than ten years ago.

Most of the people in the expert group are busy with vaccine preparation. I can't help. I can only do something within my power in this kind of tracing work, hoping to help them in their work.

Fortunately, my mother is safe and sound, my father must bless her in the sky.

November 9, 20X7

The reagents were finally extracted today, and if everything goes well, I will probably be able to conduct test experiments soon.

In fact, the work I do is essentially the same as Lee, except that his reagent is designed to stimulate the gene expression of SIRT1, and my reagent is more universal. I hope it can promote the expression of self-repair and self-purification genes.

The DNA length of a human cell is 1.8 meters, but in fact the expressed part is only a few percent of it. I used to guess the role of the other genes when I was young, and I did some explorations with the help of my instructor. , Found some interesting gene fragments.

Those unexpressed genes that were once considered redundant are the gifts of a long evolutionary process of millions or even hundreds of millions of years. I even found some fragments in it that are the same as individual fungi.

The evolution of life is to adapt to the environment and survive better. Under the fierce competition of nature, life rarely performs meaningless behaviors, especially those that require energy and material consumption. I once thought, what is the point of retaining these redundant genes?

I didn't have an answer to this question until I accidentally saw green algae in the petri dish that should have absorbed visible light, gradually turning red at the bottom of the petri dish. When the environment is different, low-level organisms such as algae will selectively express different genes.

At that time, I had a bold guess that these redundant genes are completely regarded as a library of alternative solutions, and our body will choose an appropriate solution from these redundant genes for expression according to the external environment.

Some genes are so far away from us in the history of evolution. Gradually, they are like things sinking into the depths of the database, and it is always difficult for us to touch them in the general changing environment. I believe that once you find the right switch, even the gene fragments that have been in the dust for hundreds of millions of years will be seen again.

My doctoral dissertation was on this subject, but time and energy were limited at the time, and I did not explore further. Later, in the later period of the cooperation with Lee, we discussed a part of it. Finally, because of our parting ways, we didn’t stop it. After I returned to China Soon, something like this happened to Xiao Zhao, and it never went on.

But I can be sure that my theory is correct. At least during my Ph.D. I have verified part of the correctness. Lee provided me with ideas on the expression of SIRT1 stimulation. Many animals have self-repair mechanisms after their bodies are damaged, and what I want to open is the genetic lock on this part of the human body.

And the reagent I found is this key, which is even more universal. In the process of changes in gene expression of cyanobacteria, I discovered a large number of special substances, which are the main components of this reagent. The inspiration for extracting these reagents came entirely from Lee's laboratory.

It can promote the expression of the most suitable and most needed genes in living organisms. If we have to name this gene reagent, I think it should be called adaptor A, because it exists to allow organisms to adapt to the environment.

Regarding Xiao Zhu's situation, there is currently no medical method to repair those damaged nerve cells. Even the most advanced technology can only guarantee that his physical condition will stay in the present state forever.

Adaptation A should be able to stimulate the self-repair genes in his body, and many animals have even improved their state after self-repair. If my guess is not wrong, the vitality of the newly born cells will even be restored to the best time before it was damaged. There will be no change in Xiaoxiao's vital characteristics compared to before the accident.

If all goes well, Xiao Xiao really hopes to wake up in a healthy and intact state. God bless everything goes well!

January 26, 20X7

Today is the Spring Festival, but unfortunately it is very warm even in the north this winter. I don't even want to wear a down jacket. If my mother must keep me warm, let alone snow.

It was a warm Spring Festival. My mother and I went to the freezer to see Xiao Zhao. He looked like he was asleep, no different from before.

When I took my mother to my side, I had already told her of my plan, and she had no objection. Everything is moving in a good direction, the experiment went smoothly, and it was only a matter of time before Xiao Xiao woke up.

April 2, 20X8

The weather is getting hotter and hotter, and the drought in the south has lasted for a long time. I think it is not only the weather, but also the hearts of the people!

I don’t know why this S injection will be popular as a health supplement in the market in just one year! Is everyone crazy? ! Shouldn't gene-related injections be more cautious? Such a short period of time is even shorter than the time stated in Lee's plan! I simply doubt whether he has completed human clinical trials.

The dissenting papers I submitted to the magazine were all rejected, and the remarks I published on my blog were frequently attacked. I even voted for some agencies and departments that I didn’t want to deal with, but they all fell to the bottom. I don’t understand what’s going on in this society. Up? Such terrible weather is very hot, and yellow warnings have appeared for many consecutive days, but I feel cold in my heart. I know that something is out of control. I saw it, but I couldn't stop it.

July 17, 20X8

There are all over the world with news of S injections, even overshadowing the disaster in the south. I don't understand why such injections, which can't even detect hidden dangers, have caused such a big pursuit.

Lee actually represents Glaxo's cooperation with domestic pharmaceutical companies as a Chinese. What I did not expect is that the price of S injection, which is outrageous enough to be comparable to diamonds, will be sold out of stock, and there will also be domestic products. My colleagues knew that Lee and I came to my door and wanted to get some S injections.

Maybe I am too cold and sober.

In the ancient times, those outstanding emperors, among the dragons and phoenixes, could not bear life and death. They asked for longevity or for the sake of the people and wealth or seeking immortals?

Today's standard of living has far surpassed that of the past. The advertisement of S injection directly reads "Help you realize a dream that an emperor never realized."

I can only laugh bitterly, it is true... Those emperors who want to live longer, but because of misbehavior, toss their lifespan in vain. Not to mention the side effects of S injection, but at least in terms of prolonging life, at least it is better than those Taoist priests practiced. The elixir must be reliable.

September 12, 20X8

Except for the more and more popular S injection, the world still looks unchanged. In fact, everything is changing rapidly. The price of oil is getting higher and higher, the price of goods is rising, and the weather is getting more and more abnormal. At this time last year, there were heavy rains this year. Before the rain fell, the price of food rose to such an extent that the mother had to carefully consider cooking and buying vegetables.

I often think of the story of frogs boiled in warm water. The world is changing little by little. We frogs in warm water have been busy numbly without noticing it.

By the time I noticed it, I myself had fallen into an economic crisis.

If it weren't for the support of previous patent income from abroad, I'm afraid that my small private laboratory will no longer be able to operate. In order to maintain the experimental plan, I had no choice but to quit the two assistants and other logistics staff, and sold some of the equipment, leaving only Lily, who followed from abroad and returned to China, and an elderly aunt who was doing sanitation. .

I received Lee’s email again. The generous treatment he promised really moved me for a moment. Maybe he received some news and wanted to help me. Maybe he was for Xiao Xiao’s sake. I thought about it for a while, and finally Or deleted this email, maybe I still maintain the naivety of the so-called "everyone is drunk and I am alone"?

I do not know. I only know that if I can persist, I will never compromise with an idea that I don't admit.

February 8, 20X9

This day makes no difference to me. Just after the Spring Festival, even if it is to maintain the experiment and reduce funds, the festive atmosphere still exists in my small laboratory.

Lily posted the inverted word "Fu" on the wall, which means good fortune. Each door has a red couplet, and even a red-clothed lucky cat is on the desk. She even carefully gave me a small red pendant, saying it was an amulet that could pray for safety and security. I thanked her and hung it on the wall next to the desk.

Looking back, I was surprised to see a few people in green clothes in this red atmosphere. A few greens in a piece of red, a bit of joy. But my first reaction was that trouble came to my door.

But the visiting Colonel Ye made me change my exaggerated impression of those departments. Maybe it's because he came from the military and he speaks and does things more directly and neatly?

At least I am willing to believe his statement, but I am not willing to deal with those officials. I learned later that this Colonel Ye was still an alumnus with me, and that we were still in the same class. Perhaps we are all people with the same creed, and we all believe that "doing is better than words", so we can build trust in a few words when we first meet.

His intention is very simple. He expects me to join a team of experts to study a case.

I can honestly say that my major is biology, and I am studying for a PhD in genetic engineering. From his description, he may need an epidemiology expert. The symptoms are somewhat similar to the epidemics in the disaster area the year before. I can recommend Professor Yau to him.

His expression was very cautious. I saw the soldiers following him move to the door and window respectively, and the atmosphere became tense, which made me feel very uncomfortable.

Then he told me a fact that shocked me. After this case was infected with the virus, I don’t know why the incubation time was abnormally long and the outbreak broke out abnormally fast. When the family arrived at the hospital, they had stopped breathing. The rescue was also ineffective, but in the end, miraculously, this man survived, only in a terrible way...

After listening to his description of his condition, I couldn't help but ask absurdly: "The walking dead (the walking dead, or zombies)?"

What's more frightening is that this is not the only case. The Colonel Ye explained to me sorry that he could not show me any written materials due to confidentiality regulations. He said that he can vouch for me with his own personality and the badge on his hat, and all he stated were facts he had seen with his own eyes.

I fell into contemplation for a while. The existence of zombies has always been controversial in academia, but some people have indeed verified theoretically that when the human brain consumption is reduced to a minimum, it can indeed maintain that weird state, but it needs the most attention. In fact, it is another terrible question: "Is this state contagious?"

After all, in countless movies and TV series, this terrible disaster will spread like a plague. In many cases, seemingly absurd works of art may contain some true conjectures.

But this Colonel Ye was silent. His answer is not certain, and further confirmation is needed. He hopes that I can join.

I didn't understand it at all, I told him directly, if this is a variant of that virus, it is far beyond the scope of my research. Perhaps in the eyes of laymen, the people who are engaged in genetic engineering, virus research, and epidemic disease transmission research are all in the same group. In fact, we are far apart. Even the fields of epidemiology and virus research are very different.

I have said so much, but in fact I just want to tell him that I can't do anything about this, or to put it mildly, I have powerlessness.

He finally threw a bomb at me reluctantly. Those cases had been injected with S injections before, and the senior officials of Glaxo had been secretly monitored by the intelligence department of Country A, but it was useless and they did not expect it. When this happens, there is no plan to deal with it.

Suddenly, I suddenly thought of the second half of the advice of the mentor back then, if you arbitrarily set foot in God's forbidden zone, you must be prepared to bear God's revenge.

How many people in the world have injected that **** S injection? The Glaxo company that makes a lot of money doesn’t know it. God’s revenge is really in response to the sentence: "If you don’t believe me, look up, God forbid. Who passed!"

Colonel Ye's tone was very sincere. I was indeed one of the few people who resolutely opposed the promotion of S injection. However, I only oppose the promotion of an unknown gene product based on my own criteria. Of course, I cannot foresee such terrible consequences. Otherwise, I would never let Lee behave like this, not just for so many lives, even for the mentor’s sake. I will resolutely clean up the door after I clear my name.

I implore him to give me a few days to think about it. I need to calm down and think about this issue carefully. After all, if I join this group, what will happen to my mother and what will happen to Xiao Xiao? This requires me to think carefully.

Colonel Ye is indeed very sincere. He told me that they have set up such a team at a base codenamed "Dawn", which is composed entirely of military personnel. He promised to give me the greatest degree of trust in research. And freedom, I don’t have to worry about anyone scheming.

I looked at the laboratory conditions he showed, and it was indeed very good. It was almost the same as the experimental conditions when I was studying in Country A. This Dawning base is really not easy.

He even told me that Suguang Base is willing to provide Xiaoxiao with a better freezing location, and his mother can also settle down there. In addition to group research and research, they can let me conduct Xiaoxiao’s experiments. Only the final results of the base are available. Priority application right will do.

I have to admit that I was moved.

My research direction is exactly the same as Lee’s, but he later switched to SIRT1. I have been obsessed with the problem of redundant genes first, and only recently did I have the idea of ​​adaptor A. The problems he brought to me, It is a huge and novel challenge. And from a moral point of view, Lee's failure is actually my failure, the failure of the entire genetic engineering community, and we all have the responsibility and obligation to correct it.

On the other hand, I know that now that prices are still rising wildly, I don’t know how long I can hold on to that little capital.

I called my mother in front of Colonel Ye and asked her if she would like to live in a different environment, which is simpler.

When my mother was getting older, she seemed to have a kind of wisdom accumulated over the years. She didn't ask me what happened, but quietly pondered for a while, and asked me if Xiaozhao could also go. I said yes, and she said yes.

I hung up and nodded to Colonel Ye.

He came here really well, not only with sincerity, but with enough homework, even the speed of drawing out the agreement was first-class fast. When I signed the stack of agreements, my hands were a little sour. I didn’t read the clauses verbatim, because I knew that if we succeeded, Colonel Ye will not be in a lower position in the future, and I will naturally not be treated badly. If we fail Now...no need to talk about it anymore.

Yes, we, now I have also boarded the ship of Dawn Base. Even though I don't understand politics or the rules and regulations of the system, I can smell something from Colonel Ye's urgent attitude. I'm afraid that more than one Dawn base has similar plans. From the conviction of this Colonel Ye, I am willing to choose him.

The author has something to say: After writing my brother’s diary, I can probably start the doomsday OTZ... I thought that everyone was not interested in the previous setting, so I didn’t mention those details... But I wrote it down by myself. Too much in line with the spirit of the diary ==

The first person is a bit uncomfortable. Those details mentioned in it, pseudo-scientific YY, everyone will take a look at 23333